Esophageal atresia

Person in charge:

F. Gottrand  


Esophageal atresia (EA) is the most frequent digestive malformation occurring in ~1:3,000 births worldwide. Since the first successful primary repair in 1941, postoperative outcomes have changed. With the exception of patients suffering from severe associated malformations, improvements in operative and perioperative care issues evolved from mortality to morbidity and quality of life issues. Esophageal atresia is no more a neonatal surgical problem but a long life problem. Indeed, respiratory problems, nutritional and gastroenterological issues are the most prevalent not only in the first years of life but also in adolescence and adulthood. There is a lack of recommendation and research in this moving area and multicentric collaborations are needed to answer many nowadays unanswered questions.

Projects and other activity:

The first objective of the working group is to help and organise the NASPGHAN/ESPGHAN consensus on digestive and nutritional problems in EA. Two face-to-face meetings have been organized in October 2014 (Rotterdam) and February 2015 (Boston) to prepare the consensus and vote the statements. The following projects are to identify scientific question and clinical research projects (i.e. Barrett’s esophagus, eosinophilic esophagitis).

Report of the first meeting in June 2014 in Jerusalem, Israel:

This closed meeting was oriented on methodology issues (defining the questions, literature research and grading, voting process) for the joint consensus.