ESPGHAN Masterclass on Gastrointestinal Immunology

Application Deadline: 21.09.2017

Registration Fee

Registration Fee (100.00€)

ESPGHAN Master Class On Gastrointestinal Immunology

The intestine is the biggest immunology organ in the body. Immunology related disorders, like coeliac disease, Crohn’s disease, ulcerative colitis and food allergy represent an important part of the burden of paediatric gastrointestinal illness. The field of gastrointestinal immunology is continuously expanding and it is important for the paediatric gastroenterologists to improve their knowledge and understanding of the mechanisms causing the diseases they are daily dealing with. The aim of this Master Class is to fill this gap of knowledge, using both classical and modern interactive educational tools.

APPLICATION PROCEDURE/Selection of participants:
Candidates will be selected based on
1) Personal statement - how the CD Master Class will facilitate the patient care delivered by the applicant and his/her interest in GI Immunology related diseases.
2) Brief CV

3) Delegates that will submitt a research paper or case report will be prioritized in the application process.

Target Group

Priority will be given to Paediatric Gastroenterologists, both juniors and seniors. Paediatric Gastroenterologists in training are welcome. The Event should be open to interested Immunologists, Gastroenterologists and Paediatricians.

Registration Fee
Acceptance to the Master Class will cover all accommodation costs from an Educational Grant provided to ESPGHAN. Registration includes: Attendance to scientific sessions, meeting material, attendance certificate, and accommodation for 2 nights, lunches, dinners, coffee-breaks and cultural programme. All delegates can reimburse up to 200 EUR travel costs after the course.


Organizing Committee:

Luisa Mearin

Leiden University Medical Center  
Leiden – The Netherlands

Hankje Escher


Rotterdam – The Netherlands

Carmen Ribes-Koninckx

La Fe Children´s Hospital

Valencia - Spain


Raanan Shamir   

Schneider Children's Medical Center of Israel    

Petah Tikva - Israel

Gerd Bouma   


Amsterdan – The Netherlands

Robbert Bredius   

Leiden University Medical Center   

Leiden – The Netherlands

Glenn Furuta   

Children’s Hospital

Colorado    Colorado - USA

Bana Jabri   

The University of Chicago   

Chicago, USA

Frits Koning   

Leiden University Medical Center   

Leiden – The Netherlands

Nicollette Moes
University Medical Center Antwerp (UZA)
Antwerp, Belgium

Michal Mokry   


Utrecht – The Netherlands

Edward Nieuwenhuis   


Utrecht – The Netherlands

Lissy de Ridder   


Rotterdam – The Netherlands

Edmond Rings   

Leiden University Medical Center  

Leiden – The Netherlands

Janneke Samsom   


Rotterdam – The Netherlands

Ludvig Sollid   

University of Oslo   

Oslo - Norway

Joachim Schweizer  

 Leiden University Medical Center   

Leiden – The Netherlands

Riccardo Troncone   

University Federico II   

Naples - Italy

ESPGHAN Master Class on Gastrointestinal Immunology

Day 1 – Thursday, November 16, 2017

16.00-16.45 Arrival and Registration
16.45-17.00  Welcome - Raanan Shamir, ESGPHAN President
17:00 - 17:15  Welcome and Overview, Organising Committee (Hankje Escher, Luisa Mearin,
 Carmen Ribes)

Session 1:     The Gastrointestinal (GI) System: Function and Immunology
Chair: Hankje Escher

17.15-17.30       Quiz (Edward Nieuwenhuis)
17.30- 17.55      The GI function in Health and Disease (Edmond Rings)  
17.55-18.20       The GI Immune Cells and Tissues (Janneke Samsom)  
18.20-18.45       Cytokines & Lymphokines (Antonio Garrote)
19.00                Dinner at Hampshire Hotel Leiden

DAY 2 – Friday, November 17, 2017

Session 2:         The Basics and the Clinic 1
Chair:      Carmen Ribes      

08.30-08.55     The Innate GI Immune Response (Bana Jabri)
08.55-09.20     The Adaptative GI Immune Response (Ludvig Sollid)
09.20-09.45     The role of the epithelium in the immune response (Edward Nieuwenhuis)

09.45-10.15     Coffee break

Session 3:        The Basics and The Clinic 2
Chair:  Edmond Rings

10.15-10.40     The Immunology of IBD (Gerd Bouma)
10.40-11.05     The Immunology of Coeliac Disease (Frits Koning)
11.05-11.30     2 Cases Coeliac Disease ( moderator Luisa Mearin)
                           Coeliac Disease: A Case Report (Raanan Shamir)
                           A Tricky Case: Coeliac or Not? (Roberta Mandile)
11.30-11.55     Genetic aspects of GI Immunology (Michal Mokry)
11.55-12.30     2 Cases IBD (moderator Hankje Escher)
                           SCT in Refractory Crohn's Disease( Nóra Judit Béres)
                           IL-2Rbetha mutation in VEO-IBD (Edwin de Zoeten)

12:30-13.30        Lunch

Session 4:     The Basics and The Clinic 3
Chair: Frits Koning

13.30-13.55       Oral Immunization and Tolerance (Riccardo Troncone)
13.55-14.20       2 Cases Food Allergy/Eosinophilic Diseases ( moderator Edward Nieuwenhuis)
                             Eosinophilic Gastroenteritis (Andy Darma)
                             Eosinophilic Duodenitis (Catalina Ortiz)
14.20-15.30       Carroussel with interactive presentation of cases
                             (Joachim Schweizer, ……, Robbert Bredius, Nicolette Moes, Janneke Samsom,
                              Hankje Escher)
 Group A
14.20-14.40 Station 1 case of VEO-IBD
14.45-15.05 Station 2 case of Gastrointestinal GVHD
15.10-15-30 Station 3 case of autoimmune enteropathy

Group B
14.20-14.40 Station 2 case of Gastrointestinal GVHD
14.45-15.05 Station 3 case of autoimmune enteropathy
15.10-15-30 Station 1 case of VEO-IBD

Group C
14.20-14.40 Station 3 case of autoimmune enteropathy
14.45-15.05 Station 1 case of VEO-IBD
15.10-15-30 Station 2 case of Gastrointestinal GVHD

15.30-16.00    Tea break

Session 5:        Basics BREAK OUT to the lab
16.00-18.10    2 interactive stations rotation to laboratory with demonstration of lab immunology techniques.
Station 1: Frits Koning and Lab
Station 2:
Janneke Samsom and Lab

19.00-20.30       Social Event - Leiden
20.30                  Dinner at Faculty Club Leiden

DAY 3 – Saturday, November 18, 2017

Session 6:        New and Future Developments 1
Chair: Janneke Samson

08.30-08.50    Immunosuppression and immunomodulation in  IBD (Lissy de Ridder)
08.50-09.15    Primary Immunodeficiencies (Robbert Bredius/Nicolette Moes)
09.15-10.05    The Immunology  of Eosinophilic Gastrointestinal Diseases (Glenn Furuta)
10.05-10.30    New and Future In Coeliac Disease (Frits Koning)

10.30-11.00    Coffee break

Session 7:        New and Future Developments 2
Chair: Luisa Mearin

11.00-11.25        New and Future In IBD (Janneke Samsom)
11.25-11.50        New and Future In Eosinophilic Gastrointestinal Diseases (Glenn Furuta)
11.50-12.05       Pitch your project 1: Histological Characteristics of IBD in Infants and Toddlers.
                                                                 (Elena Cernat)

12.05-12.20       Pitch your project 2: Prevalence of Autoimmune Diseases in Pediatric IBD.
                                                                 (Victoria Merrick)

12.20-12.35        Pitch your project 3: Antidepressants in Pregnancy and Intestinal Inflammation  in Rats.
                                                                (Katherine Prowse)

12.35-12.50        Pitch your project 4: Zebrafish Model Interaction Immunology and Microbiome in Obesity.
                                                                 (Alfonso Rodriguez Herrera)
12.50-13.05       Quiz (Edward Nieuwenhuis)
13.05-13.35       Summary  and Closing Remarks (Luisa Mearin)

 13.35                  Lunch and departure

The ESPGHAN Master Class on Gastrointestinal Immunology (16-18 November, 2017) has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) to provide the following CME activity for medical specialists. ESPGHAN Master Class on Gastrointestinal Immunology 2017 is designated for a maximum of, or up to 12 European CME credits (ECMEC®s).

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