ESPGHAN Monothematic Conference on The Gastrointestinal, Hepatologic and Nutritional Aspects of Cystic Fibrosis

Application Deadline: 17.02.2019

Registration Fee

Registration Fee (100.00€)

ESPGHAN Monothematic Conference on The Gastrointestinal, Hepatologic and Nutritional Aspects of Cystic Fibrosis – April 4-5, 2019 - Valencia (Spain)

Exciting and significant new developments and advantages in the diagnosis, treatment and patient prognosis of cystic fibrosis (CF) have been achieved in recent years. However, CF remains a highly prevalent, multi-organ and severe life-limiting genetic disorder with important gastrointestinal, hepatologic and nutritional implication in children. And with the improved treatment of the pulmonary complications of cystic fibrosis (CF), gastrointestinal nutritional problems have become more important in the morbidity of CF patients. 


The CF phenotype results from mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. As a result, the CF patients have, besides progressive lung disease several gastrointestinal, hepatologic and nutritional complications leading to a negative impact on disease evolution and life expectancy. 


In recent years there has been a huge and significant progress in the knowledge of the disease regarding genetics, pathogenesis, medical and nutritional management, new treatments, personalized medicine and patient self-management.  


The aim of this Monothematic Conference on CF is, by using classical as modern interactive educational tools, to give a comprehensive overview on the current status and new development  regarding the disease, in particular its gastrointestinal, hepatologic and nutritional  implication to provide a broad practical and scientific insight into recent findings in the field. 


Travel and accommodation: Participants are expected to pay their own travel,  and to pay a nominal fee of 100€ for the course.  ESPGHAN will cover a maximum of 2 nights’ accommodation, catering as well as social activities during the meeting. 

Registration fee: 100 EUR 

Applications: Application should include short CV and  experience in CF management will be valued

Please note that selected applicants will be invited to submit a case report they would like to present during the course.

Should you need assistance with your application, please contact ESPGHAN office

ESPGHAN Monothematic Conference on The Gastrointestinal, Hepatologic and Nutritional Aspects of Cystic Fibrosis – April 4-5, 2019 - Valencia (Spain)

Thursday 4 April   


Coordinators: Carmen Ribes-Koninckx, Frank Bodewes and Michael Wilschanski 


13:00-14:15 Arrival, registration and lunch 

14:15 Welcome (Carmen Ribes-Koninckx) 


14:30 – 16:00 SESSION 1: GENERAL ASPECTS Update 

Chair: Carmen Ribes-Koninckx, Frank Bodewes 

14:30 CFTR update 2019: A special focus on GI pathology (Michael Wilschanski) 

15:00 CFTR mutations: impact on pancreatic function (Isabelle Scheers)   

15:30 New Born Screening:  GI and Nutritional aspects. Consequences for early CFTR modulation treatments (Anne Munck)  

16:00 Coffee Break 


16:15 – 18:15 SESSION 2: A CLINICAL VIEW 

Chairs: Michael Wilschanski, Jessie Hulst

16:15 CF Liver disease: from diagnosis to liver transplantation (Dominique Debray) 

16:45 Intestinal lipid absorption and bile salt regulation (Frank Bodewes) 

17:15 Dysmotility disorders in CF: much more than GERD (Etna Masip) 

17:45 Abdominal pain, differential diagnosis and management (Michael Wilschanski) 

19:00 Networking activity and dinner 


Friday 5 April   



Chairs:  Isabelle Scheers, Dominique Debray 

Clinical cases presented by the delegates 

Selected abstracts (total 6)  



Chairs: Anne Munck, Michael Wilschanski 

9:30 How to assess nutritional status? Anthropometry and biomarkers (Jessie Hulst) 

10:00 How to deal with malnutrition? (Jessie Hulst) 

10:30 Coffee Break 

11:00 Bone disease in cystic fibrosis: new pathogenic insights and novel therapies (Sophie Guerin) 

11:30 CF-related glucose metabolism and impact on nutrition (Dimitri Declercq) 

12:00 Nutritional recommendations: Diet and PERT (Inês Asseiceira)  

12:30 Lunch 



Chairs: Carmen Ribes, Jessie Hulst 

13:30 New evidences and opportunities on PERT. MyCyFAPP H2020:  

13:30-13-40 MyCyFAPP: Innovative approach for nutrition and PERT self-management in CF (Carmen Ribes) 

13:40-14:00 New evidence-based method to adjust PERT (Joaquim Calvo Lerma) 

14:00-14:15 Lessons learnt from MyCyFAPP clinical trial (Paula Crespo Escobar) 

14:15 Pancreas transplantation, does it have a place in CF treatment? (Frank Bodewes) 

14:45 Do CFTR modulator therapies improve GI outcomes? (Michael Wilschanski) 

15:00 Stem cell-derived organoids to model gastrointestinal facets of cystic fibrosis and to evaluate new therapies outcomes (Karin de Winter) 

15:30 End of the course & Farewell 

Course director : 

Carmen Ribes, Spain 


Course organisers: 

Frank Bodewes, the Netherlands 

Carmen Ribes, Spain 

Michael Wilschanski, Israel 



Ines Asseiceria , Portugal 

Joaquim Calvo, Spain 

Paula Crespo, Spain 

Karin de Winter, the Netherlands 

Dominique Debray, France 

Dimitri Declerq Belgium 

Sophie Guerin, Switzerland 

Jessie Hulst, Canada 

Etna Masip, Spain 

Anne Munck, France 

Isabelle Scheers, Belgium 

Maria Roca Llorens