3rd Liver Transplantation School

Application Deadline: 04.08.2019

Registration Fee

Young ESPGHAN Regular Fee (250.00€)

ESPGHAN Member Regular (350.00€)

Non Member Regular (550.00€)


Organizers: Dominique Debray, Henkjan Verkade, Nedim Hadzic

Location: the venue/hotel is located north of Paris, approximately 30min drive from Charles de Gaulle Airport (CDG).

Online application for this school is closed. 

Late applications may be considered when sent by email to office@espghan.org. Please ensure your documents are sent as PDF Files. As case presentations have been selected, an abstract is not needed for late applications.


Around 500 pediatric liver transplants are carried out in Europe each year. No standardized training or exchange of clinical standards exists. In 2015 the ESPGHAN launched a School of Pediatric Liver Transplantation (PLT) consisting in a residential course, not intended to replace the clinical training but aiming at supplementing it, focusing at the most important topics in the field and supporting the exchange of clinical experience. The 2nd ESPGHAN Liver Transplantation School took place in 2017, in the italian city of Bergamo and is now being run in a biannual rhythm.


PGHN trainees/MDs having interest in PGHAN. Senior allied health professionals willing to commit to all modules of school.


This School is organized by the ESPGHAN Paediatric Hepatology Committee and is designed to provide cutting-edge information on this critical aspect of modern hepatology. The Faculty members will provide interactive sessions on the selection process, operations, complications and the long-term care of these patients, and feedback on the delegates’ cases. The School will represent an initial step in the formal educational module for young hepatologists towards ESPGHAN Diploma in Paediatric Liver Transplantation (EDiPaeLT). This meeting should attract younger gastroenterologists and hepatologists who have an ambition to develop transplantation programs locally, but also more senior established clinicians who would like to get a state-of-the-art update in an informal setting.


Applications are invited for approximately 40 delegate places. Candidates should include their CV (up to 2 A4 pages). YOunge ESPGHAN Members and Non-Members are requested to submit a recommendation letter from a Full ESPGHAN member upon application.

ESPGHAN will cover the following for delegates

- pre-arranged accommodation up to 3 nights (single occupancy)

- pre-arranged dinners and social program

- catering throughout the course

- course material

The registration fee for the course needs to be paid upon receipt of the respective invoice.


Deadline Early Bird: June 01 2019

Please use the online applicaton form on this page.

Applications by email cannot be accepted. if you experience any issues with the online applicaton tool, please contact office@espghan.org

Successful candidates will be expected to participate in the school with their clinical or research presentations. The submission of one case for discussion is strongly recommended.

Preliminary Programme

DAY 1 - Wednesday 25 September 2019  

12:30 - 14:00 Registration and Welcome Snack

Session 1: How and who to transplant ? 

Chairs: Dominique Debray, Yael Mozer 

14.00-14.15 Welcome

14.15-14.45 What resources are required to start a liver transplantation program? Why is PLT not available everywhere ? (Henkjan Verkade) 

14.45-15.15 Main Indications : learning from registries (Ulli Baumann) 

15.15-16.15 Dilemma : Timing (focus on Biliary atresia/ALF/ Inborn errors of metabolism), contraindications to PLT and re PLT (Marianne Samyn) 

16.15-17.00 Coffee break / assignment of working groups 

17.00-18.00 Not only the liver : multiorgan transplantation (Nedim Hadzic (bone marrow, heart, lungs, pancreas), Florence Lacaille (intestine, kidney)  

18.00-19.00 Quizz (Yael Mozer, Dominique Debray) 

20.00-23.00 Dinner

DAY 2 - Thursday 26 Sept 2019

Session 2: Management while awaiting a transplant

Chairs: Ulli Baumann, Florence Lacaille

08.30-09.15 Complications of end stage liver disease (portal hypertension; ascites) (Emanuele Nicastro)

09.15-09.45 Malnutrition (Marianne Samyn)

09.45-10.15: Role of psychometry - pre- and post. How often are we missing chronic encephalopathy ? (Valerie Mc Lin)

10.15-10.45 Coffee break

10.45-11.15 Donor selection : Living-related, ABO incompatible (Sandy Feng) 

11.15 -11.45 Technical variants (split, LRDT, auxiliary, non-heart beating, domino) (Nedim Hadzic) 

11.45-12.45 Interactive cases / abstracts (Yael Mozer, Dominique Debray) 

13.00-14.00 Lunch   

Session 3 : What can go wrong post LT?

Chairs : Henkjan Verkade, Françoise Smets 

14.00-14.45 Biliary& vascular complications : What can do the radiologist ?(Stephanie Franchi)

14.45-15.30 Multiple faces of immune graft injury : hyperacute liver graft injury, T cell mediated rejection, de novo “AIH”, Antibody mediated rejection (Sandy Feng) 

15.30- 16.00 Screening DSA : When? What does it mean? What to do ? (Valerie McLin) 

16.00 -16.30 Coffee break  

16.30-17.00 Recurrence of disease: BSEP, AILD (Henkjan Verkade) 

17.00 -18.00 Histopathology : Early and late graft dysfunction; Interactive cases (Annette Gouw) 

18.00 - 19.30 Working groups: preparation of research projects 

20.00 Dinner

DAY 3 - Friday 27 September 2019

Session 4 : Other specific complications

Chairs : Marianne Samyn, Valerie McLin,

8.30 - 9.00 Viral infections : focus on CMV, HEV, HHV6, Norovirus, ParvoB19…).(Florence Lacaille)

9.00- 10.00 PTLD and other malignancies (Francoise Smets)  

 and pathological aspects of PTLD (Annette Gouw)

10.00-10.30 Interactive cases / Quizz (Yael Mozer, Dominique Debray) 

10.30-11.00 Coffee break 

11.00-11.30 Post transplant allergy (Francoise Smets)

11.30- 12.00 Non-adherence (Yael Mozer)

12.00-12.30 Long term social aspects - re-socialisation, education (Dominique Debray).

12.30-13.00 Check list for an optimal transition to adult health care services (Ulrich Baumann)

13.00-14.00 Lunch

14.00-15.00 Conceiving/Pregnancies/Child birth in PLT recipients (Michael Heneghan).

15.00 - 16.00 Working groups: preparation of research projects

17.00 Social event 


DAY 4 - Saturday 28 September 2019

Session 5: Aims for the future

Chairs: Nedim Hadzic, Dominique Debray, Henkjan Verkade 

09.00-09.30 Presentation of research projects (WG)

09.30- 10.00 Operational tolerance /immunotolerance : dream or reality ? (Sandy Feng) 

10.00-10.30 Alternatives to PLT : Stem cells, transgenes, specific therapies, …(Francoise Smets) 

10.30-11.00 Impact of revolution in genetic testing on PLT (Emanuele Nicastro)  

11.00-11.30 Coffee break  

11.30-12.15 What’s new: Overview of ongoing research in the field of PLT (Known and unknown unknowns !) (Nedim Hadzic, Ulrich Baumann)  

12.15-12.30 Conclusion and Farewell


Local Organizer

Dominique Debray, France 

International Faculty

Annette Gouw, The Netherlands

Emanuele Nicastro, Italy

Françoise Smets, Belgium

Henkjan Verkade, The Netherlands

Marianne Samyn, United Kingdom

Michael Heneghan, United Kingdom

Nedim Hadzic, United Kingdom

Sandy Feng, US

Ulrich Baumann, Germany

Valerie McLin, Switzerland

Yael Mozer, Israel

Local Faculty

Dominique Debray, France 

Florence Lacaille, France

Stephanie Franchi, France