ESPGHAN NEC (Necrotising enterocolitis: a state of the art research and clinical management in preterm infants)

Application Deadline: 01.10.2020



Registration Fee

2 days -ESPGHAN Members (200.00€)


2 days - Non-ESPGHAN members (300.00€)


2 days - Local delegates (150.00€)


Day Rate Thursday, Nov 26 (75.00€)


Day Rate Friday, Nov 27 (100.00€)


General Information


Necrotising enterocolitis (NEC) is a major cause of death and serious disability in preterm infants and understanding is relevant to all NICU practitioners, as well as gastroenterologists, hepatologists, and a range of Allied Health Professionals (AHPs) especially dieticians and pharmacists. Whilst NEC only affects 5-10% of very preterm infants, the fear of NEC dominates decision making on a day to day basis on the NICU. The risk of NEC is affected by and impacts on feeding rate, milk type including the use of donor human milk, the use of fortifiers or supplements including breast milk fortifiers, and other interventions such as probiotics. In the short term, up to 50% of infants with NEC require surgery, of whom half may not survive. In the longer term, NEC may result in short gut requiring prolonged use of parenteral nutrition, some of which may be provided at home. NEC has major impacts on brain development affecting long-term cognitive outcome and is likely to have a large impact on quality of life over the life-course. In recent years there has been an increase in research aimed at early prediction (using microbiomic, metabolomic and other predictors) and prophylaxis using for example probiotics or other immunonutrients. This meeting will compromise a faculty consisting of scientific and clinical experts in the prevention, diagnosis, prediction, and management of NEC as well as parents to talk about their experiences. The faculty will be international and include recognised experts in their fields. The conference will consist of state-of-the-art lectures covering the basic science of underlying mechanisms, along with clinical aspects of prevention and management. 

 

The following will be covered by ESPGHAN:


- 1 night pre-arranged accommodation (organized by ESPGHAN) for non-locals participants attending both days 

- Pre-arranged dinner for non-locals participants attending both days 

- Catering throughout the course for all participants 

- Course Material for all participants 

 

Registrations (will open on 01/03/2020): 

Registration Fees (ESPGHAN members) 2 days (Incl. dinner and accommodation) : EUR 200,00 

Registration Fees (Non-ESPGHAN members) 2 days  (Incl. dinner and accommodation) : EUR 300,00 

Registration Fees (day rate) 2 days  (Exc. dinner and accommodation): EUR 150,00 

Day rate registration – 1 day, Thursday, Nov 26th  (Exc. dinner and accommodation) : EUR 75,00 

Day rate registration – 1 day, Friday, Nov 27th  (Exc. dinner and accommodation) : EUR 100,00 


Registrations will be accepted on a 1st arrived, 1st served basis, up to a maximum of 60 delegates for the 2 days course and 20 delegates for 1 day course.  

Please be aware that the course might be full before the registration deadline.  

 

The registration fee needs to be paid upon receipt of the respective invoice. 


Optional: Please note that registered delegates will be invited to submit an abstract for a poster presentation during the event (to be sent within a month after registration approval).



PRELIMENIARY PROGRAMME


26th November Day 1 

10.00-13.00 Pre-conference meeting including original research & abstract presentations 

13.00-14.00 Arrival, registration and lunch 

14.00-16.00 3 talks + 15 minute discussion 

16.00-16.30  Tea 

16.30-18.30 3 talks + 15 minute discussion 

19.30  Dinner and networking


27th November day 2 

08.00-08.30 Breakfast/Coffee/registration 

08.30-10.30 3 talks + 15 minute discussion 

10.30-11.00 Coffee 

11.00-13.00 3 talks + 15 minute discussion 

13.00-14.00  Lunch 

14.00-16.00 3 talks + 15 minute discussion 

16.00-16.30 Tea & close 

  

Speaker/topics 

Total ~14-15 talks and panel discussions. Talks are 25 minutes and 10 minutes discussion (max 35 mins).  


Please note that titles, speakers and order might change


Is NEC a single disease: variation in the clinical presentation and pathological findings 

*Dr Janet Berrington, Senior Lecturer, Newcastle University, UK 

Gut enteroid models to improve mechanistic understanding in NEC 

*Dr Matthias Zilbauer, Senior Lecturer, Cambridge University, UK  

Microbiomic, metabolomic and HMO correlates and predictors of NEC 

Dr Chris Stewart, Faculty research fellow, Newcastle University, UK 

Gut immunohistochemistry and gene expression in NEC 

Dr Chris Lamb, Newcastle University, UK 

Molecular signaling in the prevention and treatment of NEC: Tolls and beyond 

Prof David Hackham, Johns Hopkins, Baltimore, US 

Do animal models of NEC hold translational relevance for preterm infants?  

Professor Per Sangild, Copenhagen, Denmark 

Mechanisms on the causal pathway to NEC: Blood transfusion and CMV infection? 

Professor Ravi Mangel, Emory University School of Medicine, Atlanta, USA 

Human milk - protective factors for NEC and maximising availability in donor milk  

*Professor Magnus Domellof, Umea, Sweden 

Probiotics and NEC: what strain combinations really work 

*Professor Hans van Goudoever, Amsterdam UMC, Amsterdam, Netherlands 

Surgery for NEC: laparotomy or drainage, and optimal timing of stoma closure  

Ass Professor Nigel Hall, Southampton University, UK  

Optimal nutritional management during acute NEC – high, low or no parenteral nutrition? 

*Dr Chris Van Akker, Amsterdam UMC, Amsterdam, Netherlands 

Treating NEC-induced brain injury: from gut-brain signaling to gut-brain protection  

Prof David Hackham, Johns Hopkins, Baltimore, US 

Long term nutritional management of short gut following NEC 

*Dr Jutta Koeglmeier, Great Ormond Street Hospital, London, UK 

The family experience of NEC: prolonged PN and life after discharge & panel discussion 

*Parents & NEC UK advocacy organisation and Professor Nick Embleton 

 

*ESPGHAN member  



Organising faculty 

  • Professor Nicholas Embleton 
  • Dr Janet Berrington 
  • Professor Magnus Domellof (ESPGHAN CoN chair) 


  • *Dr Janet Berrington, Senior Lecturer, Newcastle University, UK  
  • *Prof Matthias Zilbauer, Senior Lecturer, Cambridge University, UK   
  • Dr Chris Stewart, Faculty research fellow, Newcastle University, UK  
  • Dr Chris Lamb, Newcastle University, UK  
  • Prof David Hackham, Johns Hopkins, Baltimore, US  
  • *Prof Per Sangild, Copenhagen, Denmark  
  • Prof Ravi Mangel, Emory University School of Medicine, Atlanta, USA  
  • *Prof Magnus Domellof, Umea, Sweden  
  • *Prof Hans van Goudoever, Amsterdam UMC, Amsterdam, Netherlands  
  • Ass Prof Nigel Hall, Southampton University, UK   
  • *Dr Chris Van Akker, Amsterdam UMC, Amsterdam, Netherlands  
  • Prof David Hackham, Johns Hopkins, Baltimore, US  
  • *Dr Jutta Koeglmeier, Great Ormond Street Hospital, London, UK  
  • Parents & NEC UK advocacy organisation 


*ESPGHAN member