ESPGHAN NEC Masterclass

General Information

General Information

Necrotising enterocolitis (NEC) is a major cause of death and serious disability in preterm infants and understanding is relevant to all NICU practitioners, as well as gastroenterologists, hepatologists, and a range of Allied Health Professionals (AHPs) especially dieticians and pharmacists.
Whilst NEC only affects 5-10% of very preterm infants, the fear of NEC dominates decision making on a day to day basis on the NICU. The risk of NEC is affected by and impacts on feeding rate, milk type including the use of donor human milk, the use of fortifiers or supplements including breast milk fortifiers, and other interventions such as probiotics. In the short term, up to 50% of infants with NEC require surgery, of whom half may not survive.

In the longer term, NEC may result in short gut requiring prolonged use of parenteral nutrition, some of which may be provided at home. NEC has major impacts on brain development affecting long-term cognitive outcome and is likely to have a large impact on quality of life over the life-course. In recent years there has been an increase in research aimed at early prediction (using microbiomic, metabolomic and other predictors) and prophylaxis using for example probiotics or other immunonutrients. This meeting will compromise a faculty consisting of scientific and clinical experts in the prevention, diagnosis, prediction, and management of NEC as well as parents to talk about their experiences. The faculty will be international and include recognised experts in their fields. The conference will consist of state-of-the-art lectures covering the basic science of underlying mechanisms, along with clinical aspects of prevention and management.

Application & Fees

Registration Deadline: October 01, 2020
Registration Fees:

ESPGHAN Members - 2 days (Incl. dinner and accommodation) : EUR 200,00
Non-ESPGHAN Members - 2 days (Incl. dinner and accommodation) : EUR 300,00
Day Rate Registration -  2 days (Exc. dinner and accommodation): EUR 150,00
Day rate registration – 1 day, Thursday, Nov 26th (Exc. dinner and accommodation) : EUR 75,00
Day rate registration – 1 day, Friday, Nov 27th (Exc. dinner and accommodation) : EUR 100,00

Registrations will be accepted on a 1st arrived, 1st served basis, up to a maximum of 60 delegates for the 2 days course and 20 delegates for 1 day course.
Please be aware that the course might be full before the registration deadline. The registration fee needs to be paid upon receipt of the respective invoice.
Optional: Please note that registered delegates will be invited to submit an abstract for a poster presentation during the event (to be sent within a month after registration approval).

Kindly use the online application form on this page. Applications by email cannot be accepted. If you experience any issues with the online application tool, please contact Priority will be given to ESPGHAN Members. Please do not make travel arrangements before receipt of a formal confirmation of acceptance from the ESPGHAN Office.

The course language is English.


Day 01 - Thursday, November 26

10.00 – 13.00

Pre-conference meeting incl. original research and abstract presentations 

13.00 – 14.00

Arrival, Registration, Lunch

14.00 – 16.00

3 talks & 15 min discussion
16:00 - 16:30


16.30 – 18.30

3 Talks + 15 min discussion


Dinner & Networking

Day 02 - Friday, November 27

08.00 – 08.30


08.30 – 10.30

3 Talks + 15 min discussion

10.30 – 11.00

Coffee Break

11.00 – 13.00

3 Talks + 15 min discussion
13:00 - 14:00


14.00 – 16.00

3 Talks + 16 min discussion

16:00 - 16:30

Tea & Close

Faculty & Topics

Is NEC a single disease: variation in the clinical presentation and pathological findings
*Dr Janet Berrington, Senior Lecturer, Newcastle University, UK

Gut enteroid models to improve mechanistic understanding in NEC
*Dr Matthias Zilbauer, Senior Lecturer, Cambridge University, UK

Microbiomic, metabolomic and HMO correlates and predictors of NEC
Dr Chris Stewart, Faculty research fellow, Newcastle University, UK

Gut immunohistochemistry and gene expression in NEC
Dr Chris Lamb, Newcastle University, UK

Molecular signaling in the prevention and treatment of NEC: Tolls and beyond
Prof David Hackham, Johns Hopkins, Baltimore, US

Do animal models of NEC hold translational relevance for preterm infants?
Professor Per Sangild, Copenhagen, Denmark

Mechanisms on the causal pathway to NEC: Blood transfusion and CMV infection?
Professor Ravi Mangel, Emory University School of Medicine, Atlanta, USA

Human milk - protective factors for NEC and maximising availability in donor milk
*Professor Magnus Domellof, Umea, Sweden

Probiotics and NEC: what strain combinations really work
*Professor Hans van Goudoever, Amsterdam UMC, Amsterdam, Netherlands

Surgery for NEC: laparotomy or drainage, and optimal timing of stoma closure
Ass Professor Nigel Hall, Southampton University, UK

Optimal nutritional management during acute NEC – high, low or no parenteral nutrition?
*Dr Chris Van Akker, Amsterdam UMC, Amsterdam, Netherlands

Treating NEC-induced brain injury: from gut-brain signaling to gut-brain protection
Prof David Hackham, Johns Hopkins, Baltimore, US

Long term nutritional management of short gut following NEC
*Dr Jutta Koeglmeier, Great Ormond Street Hospital, London, UK

The family experience of NEC: prolonged PN and life after discharge & panel discussion
*Parents & NEC UK advocacy organisation and Professor Nick Embleton

*ESPGHAN member

Cost Coverage

ESPGHAN will cover the following for delegates:

- 1 night pre-arranged accommodation (organized by ESPGHAN) for non-locals participants attending both days
- Pre-arranged dinner for non-locals participants attending both days
- Catering throughout the course for all participants
- Course Material for all participants


If you have any questions, please contact the ESPGHAN Office for details.
Phone: +41 (0)22 9000 401