Masterclass in GI Immunology

November 17 - 19, 2022

General Information

The intestine is the largest immunological organ in the body. Disorders related to immune dysfunction, such coeliac disease, Crohn’s disease, ulcerative colitis, and allergy/eosinophilic disorders are common in the Paediatric Gastroenterology practice.
For Paediatric Gastroenterologists however there is a lack of educational activities concerning the immunologic mechanisms of these diseases.
The aim of this Master Class is to fill up this gap of knowledge, and  help clinicians to better understand the aetiology and treatments. The program will be interactive and informal. After the great success of the 1st Masterclass in 2017 that was held in Leiden, we are now proud to organise the 2nd Masterclass in Rotterdam, the Netherlands.

This school is supported by the ESPGHAN Education Partner Programme.

COVID-19 Information

This school is planned for onsite participation only. We will be carefully monitoring the situation in The Netherlands and international COVID-19 regulations. ESPGHAN reserves the right to postpone/cancel the course or change its current format if deemed necessary to protect the health of our delegates, faculty and staff.

For more information please contact the ESPGHAN Office.


Registration & Fees

Registration Deadline: we have reached our maximum capacity for this course. By registering, you will be added to our waiting list and contacted if a spot becomes vacant.

Registration fee: EUR 100.00
A standard fee of EUR 100 will apply to attend the course.

Kindly use the online application form on this page. Registrations submitted by email cannot be accepted. If you experience any issues with the tool, please contact us at office@espghan. Registrations will be based on a first-come, first-served basis. ESPGHAN keeps the right to close registration before the above stated deadline if capacities are reached.

Please do not make travel arrangements before receipt of a formal confirmation of acceptance from the ESPGHAN Office. 


Preliminary Programme

Day 01 - November 17

16.00-16.45    Arrival and Registration


16.45-17.00    Welcome 

17:00 - 17:15  Welcome and Overview, Organising Committee 

Session 1:        The Gastrointestinal (GI) System: Function and Immunology

17.15-17.30     Quiz (Edward Nieuwenhuis)
17.30-17.50     GI Immune Cells and Tissues (Janneke Samsom) 
Monogenic IBD - from bedside to the lab and back to the patient (Dror Shouval)


19.00                Dinner at INNTEL Hotel Rotterdam

Day 02 - November 18

Session 2:        The Basics and the Clinic 1
Chair:   Carmen Ribes-Koninckx     
08.30-09.00     The Innate GI Immune Response (Valentina Discepolo)

09.00-09.30     The Adaptative GI Immune Response (Vincent van Unen)

09.30-09.50     Clinical Case

09.50-10.15     Coffee break

Session 3:        The Basics and The Clinic 2

Chair:   Luisa Mearin

10.15-10.45     New insights into environmental factors as mediators of inflammation in IBD (Dror Shouval)

10.45-11.00     Clinical Case

11.00-11.30     The Immunology of Coeliac Disease (Frits Koning)
11.30-11.45     Clinical Case

11.45-12.15     Genetic aspects of Gastrointestinal disease (Iris Jonkers)

12:30-13.30    Lunch

Session 4:     The Basics and The Clinic 3
Chair: to be confirmed
13.30-14.00     New insights into diet and inflammation in IBD (Johan van Limbergen)

14.00-15.30     Clinical carrousel with 3 stations (2 experts per station, 25 minutes per round)
15.30-16.00    Tea break

Session 5:        BREAK OUT to from lab to clinic or vice versa (2 groups)
Group 1 (lab to clinic):

16.00-17.00     station with laboratory setting with demonstration of lab immunology techniques

17.00-18.00     group tour to Children’s Hospital, medical faculty, library

Group 2 (clinic to lab):

16.00-17.00     group tour to Children’s Hospital, medical faculty, library

17.00-18.00     station with laboratory setting with demonstration of lab immunology techniques


19.00-20.30     Networking 
20.30                Dinner 

Day 03 - November 19

Session 6:        New and Future Developments 1

Chair: Janneke Samsom

09.00-09.30    Immunosuppression and immunomodulation in IBD (Lissy de Ridder)

09.30-09.45     Clinical case

09.45-10.15    Eosinophilic disorders (Jorge Amil Dias)

10.15-10.30     Clinical case

10.30-11.00    Coffee break

Session 7:        New and Future Developments 2

Chair: Luisa Mearin

11.00-11.15    Organoids and Gastrointestinal disease (Edward Nieuwenhuis)

11.15-11.30    Case presentation or Pitch your project 1: by delegate

11.30-11.45    New and Future in immune-mediated disorders (Vincent van Unen)

11.45-12.00     Case presentation or Pitch your project 2: by delegate

12.00-12.15    Case presentation or Pitch your project 3: by delegate

12.15-12.30    Case presentation or Pitch your project 4: by delegate

12.30-12.45     Quiz (Edward Nieuwenhuis)
12.45-13.00     Summary and Closing Remarks (Hankje Escher)

13.15                Lunch and departure

Cost Coverage

ESPGHAN will arrange and cover the following for registered delegates: 

  • Accommodation up to 2 nights (organised by ESPGHAN)
  • Pre-arranged dinners and social programme  
  • Catering throughout the course   
  • Course Material 


If you have any questions, please contact the ESPGHAN Office for details.
Phone: +41 (0)22 9000 401