GI Immunology Master Class: from pathogenesis to clinical management of EGID, Celiac Disease and IBD

March 05 - 07, 2025
NAPLES, ITALY

General Information

This Masterclass aims at providing the basis for an in-depth knowledge of the etiopathogenetic events leading to immune-mediated pediatric GI diseases (EoE, EGID, Celiac Disease, Food Allergy and IBD). It will cover a wide range of topics: from the basics of the development of the mucosal immune system, to its dysregulation in the context of GI diseases. This Master Class has been designed with the endorsement of the EGID working group, the IBD Porto Group and the CD-SIG and covers most aspects of pediatric immune mediated GI diseases and could be of interest for a wide range of trainees. The class will be informal, interactive and fun.

Application & Fees

Application Deadline: January 05, 2025
Participation fees:

ESPGHAN Members (incl. Young ESPGHAN): EUR 150.00
Non-Members: EUR 200.00

Applicants need to submit a current CV, a motivation letter and an abstract (research topic or clinica case). The number of applicants is limited and delegates will be selected by the organizers after the application deadline. Priority will be given to ESPGHAN Members, in particular Young ESPGHAN Members partaking in the ESPGHAN Research Curriculum.

Kindly use the online application form on this page. Applications by email cannot be accepted. If you experience any issues with the online application tool, please contact office@espghan.org
ESPGHAN Members may attend two courses per year and non-members may attend one course before applying for society membership.

Please do not make travel arrangements before receipt of a formal confirmation of acceptance from the ESPGHAN Office.

Delegates are expected to attend the full course and arrange their travel according to the course schedule. 

The course language is English.

PROGRAMME

Preliminary Programme

Day 01 - March 05 - Back to the Basics

13:00-14:00 Registration – Networking Lunch
 

14:00-14:30 – Opening Remarks – Chair: Annamaria Staiano e Riccardo Troncone (Naples, Italy) – 5 min

Introductory Lecture: Shaping the gut: insights on the GI Immune System development (Allan Mowat, Glasgow) - 25 min

14:30 – 18:00 The key players – Chairs: Valentina Discepolo (Naples, Italy), Ludvig Sollid (Oslo, Norway)

  1. IELs and innate like cells in the gut - Bana Jabri (Paris, France) – 20 min
  2. Eosinophils and Fibroblasts in the GI tract – Amanda Muir (Philadelphia, PA, USA) – 20 min
  3. Macrophages and myeloid cells in the gut - Allan Mowat (Glasgow, Scotland) – 20 min
  4. The intestinal epithelium and its Cross-talk with the GI immune system - TBD – 20 min

10 min Q&A session

Coffee Break 30 minutes

  1. B cell and T cell responses in the gut - Ludvig Sollid (Oslo, Norway) - 20 min
  2. Mucosal regulatory T cells - Carmen Gianfrani (Naples, Italy) - 20 min
  3. What is oral Tolerance? - Bana Jabri (Paris, France) - 20 min
  4. Microbiota and its role in shaping the GI immune system – Maria Rescigno (Milan, Italy) – 20 min

10 min Q&A session
 

18:00 - Networking 

20:30 – Dinner 

Day 02 - March 06 - The Good, the Ugly and the Gut

9:00 – 11:30 - Pathogenesis of GI mucosal diseases – Chair: Bana Jabri (Paris, France), Salvatore Oliva (Rome, Italy)

  1. VEO IBD: Genetics and clinical implications - Richard Russell (Edinburgh, Scotland) – 20 min
  2. Epigenetics in IBD – Caterina Strisciuglio (Naples, Italy) – 20 min

10 min Q&A session

  1. The atopic march: pathogenesis of food allergies - Roberto Berni Canani (Naples, Italy) – 20 min
  2. Pathogenesis of EGID - Amanda Muir (Philadelphia, PA, USA) - 20 min

10 min Q&A session

  1. From genetic risk to loss of immune tolerance: the pathophysiology of CD – Ludvig Sollid (Oslo, Norway) - 20 min
  2. The exposome in celiac disease - Ketil Stordal (Oslo, Norway) – 20 min

10 min Q&A session

11:30 – 12:00 coffee break

12:00 – 13:00 – Presentation of Selected Abstracts (6 selected abstracts – 7 min + 3 min of discussion) – Chair: M. Martinelli

13:00 – 14:30 – Lunch Break

14:30 – 15:40 Clinical kaleidoscope – Chair: Ketil Stordal (Slovenia), Caterina Strisciuglio (Naples, Italy)

  1. PIBD epidemiology and clinical phenotype in 2025 - Erasmo Miele (Naples, Italy) - 20 min
  2. EGID from the endoscopy room to the bed side - Salvatore Oliva (Rome, Italy) – 20 min
  3. The natural history of celiac disease - Renata Auricchio (Naples, Italy) – 20 min

10 min Q&A session

15:40 – 16:00 Coffee Break

16:00-17:00 – Selected Clinical Cases (6 cases - 7 min + 3 of discussion) - Chair: Erasmo Miele (Naples)

 

19:00 Social Program and Dinner

Day 03 - March 07 - Thinking outside the Box

09:00 – 11:30 Prevention and Therapies - Chair: Renata Auricchio & Richard Russel (Cambridge, UK)

  1. Microbiota modulation in GI diseases (from probiotics to FMT) – Maria Rescigno (Milan, Italy) – 20 min
  2. Therapeutic approach of EGIDs - Alexandra Papadopoulou (Athens, Greece) – 20 min

10 min Q&A session

  1. Nutritional therapy in IBD - Richard Russell (Edinburgh, Scotland) - 20 min
  2. Targeting the immune system to treat IBD – Erasmo Miele (Naples, Italy) – 20 min

10 min Q&A session

  1. Therapeutic approach in celiac disease – Riccardo Troncone (Naples, Italy) – 20 min
  2. Re-establishing immune tolerance in GI diseases – Valentina Discepolo (Naples, Italy) – 20 min

10 min Q&A session

11:30 – 12:00 Coffee Break

11:00 – 13:30 Food for thoughts: the gut inside out - Chair: R. Berni Canani (Naples) – Alexandra Papadopoulou (Athens)

  1. The impact of (mal)nutrition on the immune system: from starvation to obesity – Giuseppe Matarese (Naples) – 20 min
  2. Dissecting disease heterogeneity to reach personalized medicine – Valentina Discepolo (Naples)– 20 min

10 min Q&A session

  1. How the intestinal immune system modulates distant organs – Maria Rescigno (Milan, Italy) – 20 min
  2. Disorders of the gut-brain interaction – Annamaria Staiano (Naples, Italy) – 20 min

10 min Q&A session

13: 30 - Closing Remarks - Greetings and Goodbye (Valentina Discepolo, Renata Auricchio & Riccardo Troncone)

Cost Coverage

ESPGHAN will cover the following for international delegates:

  • up to 2 nights accommodation in a pre-arranged hotel for March 05 and 06
  • pre-arranged dinners and socials
  • catering throughout the course
  • congress material

Disclaimer

Please be aware that ESPGHAN will be taking photos and/or videos at this event. By registering and attending th is course you acknowledge and agree to the terms and conditions. Details of the disclaimer will be attached to your notification email. Please contact office@espghan.org if you have any questions or concerns.

CONTACT

If you have any questions, please contact the ESPGHAN Office for details.
Phone: +41 (0)22 9000 401
Email: office@espghan.org